Newborn and Infant Nursing Reviews
Volume 9, Issue 4 , Pages 219-225 , December 2009

Transport of the Neonatal Patient With Persistent Pulmonary Hypertension

  • Peter Brust, RN, MSN, CCRN, CMTE

      Affiliations

    • Emergency Transport Services, The Children's Hospital of Philadelphia, Philadelphia, PA
    • Corresponding Author InformationAddress correspondence to Peter Brust, RN, MSN, CCRN, CMTE, Emergency Transport Services, The Children's Hospital of Philadelphia, Room 1712 South Tower, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104.
    • ,
  • Marjorie Hamburger, RN, MSN, CCRN

      Affiliations

    • The Children's Hospital of Philadelphia, Philadelphia, PA
    • ,
  • Patricia Larkin, RN, BSN, CCRN

      Affiliations

    • The Children's Hospital of Philadelphia, Philadelphia, PA

References 

  1. Abman SH. Recent advances in the pathogenesis and treatment of persistent pulmonary hypertension of the newborn. Neonatology. 2007;91:283–290
  2. Graves ED, Redmond CR, Arensman RM. Persistent pulmonary hypertension in the neonate. Chest. 1988;93:638–641
  3. Hernandez-Diaz S, Van Marter LJ, Werier MM, et al. Risk Factors for persistent pulmonary hypertension of the newborn. Pediatrics. 2007;120:e272–e282
  4. Walsh-Sukys MC, Tyson JE, Wright LL, et al. Persistent pulmonary hypertension of the newborn in the era before nitric oxide: practice variation and outcomes. Pediatrics. 2000;105:1–14
  5. Ostrea EM, Villanueva-Uy ET, Natarajan G, et al. Persistent pulmonary hypertension of the newborn, pathogenesis, etiology and management. Pediatr Drugs. 2006;8:179–188
  6. Steinhorn RH. Pulmonary hypertension, persistent-newborn. Emedicine.Medscape.Com. April 19, 2007.
  7. Andrade SE, McPhillips H, Loren D, et al. Antidepressant medication use and risk of persistent pulmonary hypertension of the newborn. Pharmacoepidemiol Drug Saf. 2009;18:246–252
  8. Koren G, Boucher N. Adverse effects in neonates exposed to SSRIs and SNRI in late gestation. Can J Clin Pharmacol. 2009;16:e66–e67
  9. Curtis J, Kim G, Wehr NB, et al. Group B streptococcal phospholipid causes pulmonary hypertension. Proc Natl Acad Sci U S A. 2003;5087–5090
  10. Steinhorn RH. Nitric oxide and beyond: new insights and therapies for pulmonary hypertension. J Perinatol. 2008;28:s67–s71
  11. Wanstall JC, Jeffery TK. Recognition and management of pulmonary hypertension. Drugs. 1998;56:989–1007
  12. Asad A, Bhat R. Pharmacology for meconium aspiration. J Perinatol. 2008;28:S72–S78
  13. Perreault T. Persistent pulmonary hypertension of the newborn. Paediatr Respir Rev. 2006;7S:S175–S176
  14. Baquero H, Soliz A, Neira F, et al. Oral sildenafil in infants with persistent pulmonary hypertension of the newborn: a pilot randomized blinded study. Pediatrics. 2006;117:1077–1083
  15. Fakioglu H, Totapally BR, Torbati D, et al. Hypoxic respiratory failure in term newborns: clinical indicators for inhaled nitric oxide and extracorporeal membrane oxygenation therapy. J Crit Care. 2005;20:288–295
  16. Soll RF. Inhaled nitric oxide in the neonate. J Perinatol. 2009;29:s63–s67
  17. Gadzinowski J, Kowalska K, Vidyasagar D. Treatment of MAS with PPHN using combined therapy: SLL, bolus surfactant and iNO. J Perinatol. 2008;S56–S66
  18. Wiedemann JR, Saugstad AM, Barnes-Powell L, et al. Meconium aspiration syndrome. Neonatal Netw. 2008;27:81–87
  19. Lowe CG, Trautwien JG. Inhaled nitric oxide therapy during the transport of neonates with persistent pulmonary hypertension or severe hypoxic respiratory failure. Eur J Pediatr. 2007;166:1025–1031
  20. Pippert G, Wewerka S, Fransonce RJ, et al. Neonatal patient sound exposure during critical care transport. Air Med J. 2008;27:234–235
  21. Tung BJ. The use of nitric oxide therapy in the transport of newborns with persistent pulmonary hypertension. Air Med J. 2001;20:10–11
  22. Lutman D, Petros A. Inhaled nitric oxide in neonatal and paediatric transport. Early Hum Dev. 2008;84:725–729
  23. ELSO Patient specific supplements to the ELSO general guidelines, 2009 April.
  24. Bassler D, Choong K, McNamara P, et al. Neonatal persistent pulmonary hypertension treated with Milrinone; four case reports. Biol Neonate. 2006;89:1–5
  25. Hosono S, Ohno T, Kimoto H, et al. Developmental outcomes in persistent pulmonary hypertension treated with nitric oxide therapy. Pediatr Int. 2009;51:79–83

 From the Emergency Transport Team of the Children's Hospital of Philadelphia.

PII: S1527-3369(09)00130-5

doi: 10.1053/j.nainr.2009.09.003

Newborn and Infant Nursing Reviews
Volume 9, Issue 4 , Pages 219-225 , December 2009

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