Newborn and Infant Nursing Reviews
Volume 7, Issue 2 , Pages 95-99 , June 2007

Neonatal Induced Hypothermia

  • Anita L. Thoerner, RN, MSN, CNP

      Affiliations

    • Corresponding Author InformationAddress correspondences to Anita L. Thoerner RN, MSN, CNP, 11587 Plumhill Drive, Cincinnati, OH 45249.

References 

  1. Volpe JJ. Hypoxic-ischemic encephalopathy: biochemical and physiological aspects. In:  Fletcher J,  Hund R editor. Neurology of the newborn. 4th ed. Philadelphia, (PA): Saunders; 2001;p. 217–276
  2. Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicenter randomized trial. Lancet. 2005;365:663–670
  3. Gunn AJ, Bennet L. Cerebral hypothermia in the management of hypoxic-ischemic encephalopathy. NeoReviews. 2002;3:e116
  4. duPlessis AJ, Johnston MV. Hypoxic-ischemic brain injury in the newborn: cellular mechanisms and potential strategies for neuroprotection. Clin Perinatol. 1997;24:627–654
  5. Low JA, Galbraith RS, Muir DW, et al. The relationship between perinatal hypoxia and newborn encephalopathy. Am J Obstet Gynecol. 1985;152:256–260
  6. Robertson CMT. Long-term follow-up of term neonates with perinatal asphyxia. In:  Stevenson DK,  Sunshine P editor. Fetal and neonatal brain injury. 2nd ed. Oxford: Oxford University Press; 1997;p. 615–630
  7. Shankara S, Woldt E, Koepke T, et al. Acute neonatal morbidity and long-term central nervous system sequelae of perinatal asphyxia in term infants. Early Hum Dev. 1991;25:135–148
  8. Robertson CM, Finer NN, Grace MG. School performance of survivors of neonatal encephalopathy associated with birth asphyxia at term. J Pediatr. 1989;114:753–759
  9. Edwards AD, Yue X, Squier MV, et al. Specific inhibition of apoptosis after cerebral hypoxia-ischaemia by moderate post-insult hypothermia. Biochem Biophys Res Commun. 1995;217:1193–1199
  10. de Plessis AJ. Induced mild hypothermia: the spearhead strategy for effective neonatal neuroprotection?. Pediatrics. 1998;102:972–974
  11. Gunn AJ, Gunn JR, Gunning MJ, et al. Neuroprotection with prolonged head cooling started before postischemic seizures in fetal sheep. Pediatrics. 1998;102:1098–1106
  12. Gunn AJ, Gunn JR, deHann HH, et al. Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs. J Clin Invest. 1997;99:248–256
  13. Gunn AJ, Gluckman PD, Gunn TR. Selective head cooling in newborn infants following perinatal asphyxia: a safety study. Pediatrics. 1998;104:885–892
  14. Shankaran S, Laptook AR, Ehrenkranz RA, et al. National Institute of Child Health and Human Development Neonatal Research Network Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005;353:1574–1584
  15. Barks, eNICUniversity Lectures. Neonatal hypothermia: what are we waiting for? 2006
  16. Higgins RD, Raju TN, Perlman J, et al. Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop. J Pediatr. 2006;148:170–175

PII: S1527-3369(07)00043-8

doi: 10.1053/j.nainr.2007.05.002

Newborn and Infant Nursing Reviews
Volume 7, Issue 2 , Pages 95-99 , June 2007

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